Why is Spyre Therapeutics, Inc. stock down today?
June 23, 2026
Spyre Therapeutics, Inc.
SYRE · NMS · USD
vs. prev. close $100.32
Last updated Jun 23, 2026 15:13
Intraday Chart — 5-min intervals
SYRE · less than a minute ago
Spyre Therapeutics, Inc. dips 0.33% — MT Newswires reports
Spyre Therapeutics, Inc. (SYRE) is drifting slightly lower, at $99. 99 — down 0. 33% from yesterday's close of $100. 32. Today's move appears driven by recent headlines, including "Deutsche Bank Adjusts Spyre Therapeutics Price Target to $135 From $115, Maintains Buy Rating" and "Update: Wedbush Raises Price Target on Spyre Therapeutics to $100 From $80 on Positive SPY002 Results, Maintains Outperform Rating". News sentiment around SYRE is leaning positive.
The broader market is under pressure (S&P 500: -1. 1%, Nasdaq: -1. 7%, Dow Jones: +0. 0%, Shanghai: +1. 8%, Hang Seng: -1. 8%). Past performance does not guarantee future results.
Key Factors
Auto-generated analysis · Not financial advice
Deutsche Bank Adjusts Spyre Therapeutics Price Target to $135 From $115, Maintains Buy Rating
MT Newswires·about 4 hours agoneutralUpdate: Wedbush Raises Price Target on Spyre Therapeutics to $100 From $80 on Positive SPY002 Results, Maintains Outperform Rating
MT Newswires·8 days agopositiveWedbush Raises Price Target on Spyre Therapeutics to $100 From $80, Maintains Outperform Rating
MT Newswires·8 days agoneutralSpyre Announces Potential Best-in-Class SPY002 (anti-TL1A) Part A Induction Results from SKYLINE Trial in Moderate-to-Severe Ulcerative Colitis Patients
GlobeNewswire·8 days agoneutralSpyre Therapeutics Announces Grants of Inducement Awards
GlobeNewswire·18 days agoneutralSYRE Completes Enrollment in SKYWAY Basket Study on SPY072, Stock Up
Zacks·19 days agoneutralDeutsche Bank Adjusts Spyre Therapeutics Price Target to $115 From $102, Maintains Buy Rating
MT Newswires·19 days agoneutralSpyre Therapeutics (SYRE): 12 Best High Short Interest Stocks With Highest Upside Potential
Insider Monkey·19 days agoneutral
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